The origin of the CCAP Nkhoma Synod goes back to the arrival of the Reverends Andrew Charles Murray and Theunis C. Botha Vlok who established the first mission station at Mvera in the territory of Traditional Authority Chiwere in Dowa district on 28 November 1889. Before 1900, the following mission stations which later became congregations were established: Kongwe (189), Nkhoma (1896) and Malembo and Livlezi were taken over from the Livingstonia Mission of the Free Church of Scotland in 1895.
Before 1924, Nkhoma Synod was called the Dutch Reformed Church Mission (D.R.C.M). It became a Presbytery in 1924 then same year when the Presbyteries of Blantyre and Livingstonia formed a federation of churches called the CCAP. Nkhoma Presbytery joined the CCAP in 1926. When the Presbyteries of Blantyre, Livingstonia and Nkhoma attained statuses of Synods in 1956, the Synod of the CCAP became the General Synod of the CCAP (later the General Assembly).
When the CCAP-Nkhoma Synod became an autonomous church in 1962, it had grown into a strong and virile Church counting 80,000 communicant members, with 34000 catechumens and 52 congregations under the leadership of 37 ordained ministers and 1236 church elders and 1236 deacons. Today the CCAP-Nkhoma Synod has close to 1million communicant church members, 235 congregations in Malawi and South Africa, 28 Presbyteries, 238 ordained church ministers, _________________church elders and ________________deacons.
Presently the Church consists of women, men and youth guilds, health, youth, education, church and society, mission, Relief and development, construction, and communication departments and Nkhoma University as well as Nkhoma Nursing College